Associated Papers
PHF8/KDM7B: A Versatile Histone Demethylase and Epigenetic Modifier in Nervous System Disease and Cancers.
Fan T et al.
Epigenomes, 2024
Functional Characterization of a Phf8 Processed Pseudogene in the Mouse Genome.
St-Germain J et al.
Genes, 2023
Variants in PHF8 cause a spectrum of X-linked neurodevelopmental disorders and facial dysmorphology.
Sobering AK et al.
Hgg Advances, 2022
Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders.
Poeta L et al.
Human Molecular Genetics, 2019
MicroRNA-655-3p and microRNA-497-5p inhibit cell proliferation in cultured human lip cells through the regulation of genes related to human cleft lip.
Gajera M et al.
Bmc Medical Genomics, 2019
31122291 (PubMed )
Supplement: 12920_2019_535_MOESM1_ESM.zip › 3_Human_Cleft_Lip__Table_S3__Significant_R2.xlsx › Single_Gene_Significant
Conformational Dynamics Underlies Different Functions of Human KDM7 Histone Demethylases.
Chaturvedi SS et al.
Chemistry (weinheim an Der Bergstrasse, Germany), 2019
JMJD-1.2/PHF8 controls axon guidance by regulating Hedgehog-like signaling.
Riveiro AR et al.
Development (cambridge, England), 2017
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.
Yatim A et al.
Molecular Cell, 2012
Plant homeodomain fingers form a helping hand for transcription.
Fortschegger K et al.
Epigenetics, 2011
The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation.
Qiu J et al.
Cell Research, 2010
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development.
Qi HH et al.
Nature, 2010
A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation.
Kleine-Kohlbrecher D et al.
Molecular Cell, 2010
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation.
Feng W et al.
Nature Structural & Molecular Biology, 2010
Structural insights into a novel histone demethylase PHF8.
Yu L et al.
Cell Research, 2010
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase.
Loenarz C et al.
Human Molecular Genetics, 2010
Screening of mutations in the PHF8 gene and identification of a novel mutation in a Finnish family with XLMR and cleft lip/cleft palate.
Koivisto AM et al.
Clinical Genetics, 2007
A Neuronal Activity-Dependent Dual Function Chromatin-Modifying Complex Regulates Arc Expression
Oey NE et al.
Eneuro, 0
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