Associated Papers
Deciphering gain-of-function from loss-of-function variants with AlphaMissense: A case study with the mechanosensitive PIEZO1 ion channel protein.
Pillai J et al.
Biochemistry and Biophysics Reports, 2026
PIEZO1 mechanical insensitivity in generalized lymphatic dysplasia with the potential for pharmacological rescue.
Ludlow MJ et al.
Iscience, 2025
PIEZO1 variant implications for biological understanding and human health.
Cheng CW et al.
Open Biology, 2025
A 3-year-old Tanzanian Female with Glucose-6-Phosphate Dehydrogenase A- and a Novel Heterozygous PIEZO1 Mutation (2744A>G, N915S) Presenting with Severe Hemolytic Anemia.
Fustino NJ et al.
Annals of African Medicine, 2024
Mechanisms of PIEZO Channel Inactivation.
Zhou Z et al.
International Journal of Molecular Sciences, 2023
Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice.
Bartoli F et al.
Cells, 2022
Mechanosensitive Piezo1 ion channel protein (PIEZO1 gene): update and extended mutation analysis of hereditary xerocytosis in India.
More TA et al.
Annals of Hematology, 2020
Dietary fatty acids fine-tune Piezo1 mechanical response.
Romero LO et al.
Nature Communications, 2019
The Molecular Basis for Altered Cation Permeability in Hereditary Stomatocytic Human Red Blood Cells.
Flatt JF et al.
Frontiers in Physiology, 2018
Functional analyses of heteromeric human PIEZO1 Channels.
Gnanasambandam R et al.
Plos One, 2018
Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis.
Glogowska E et al.
Blood, 2017
The Kinetics and the Permeation Properties of Piezo Channels.
Gnanasambandam R et al.
Current Topics in Membranes, 2017
Piezo proteins: regulators of mechanosensation and other cellular processes.
Bagriantsev SN et al.
The Journal of Biological Chemistry, 2014
The structure of a conserved piezo channel domain reveals a topologically distinct β sandwich fold.
Kamajaya A et al.
Structure (london, England : 1993), 2014
Hereditary xerocytosis and familial haemolysis due to mutation in the PIEZO1 gene: a simple diagnostic approach.
Sandberg MB et al.
International Journal of Laboratory Hematology, 2014
Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1.
Bae C et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels.
Albuisson J et al.
Nature Communications, 2013
Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis.
Zarychanski R et al.
Blood, 2012