Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.A53T
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PIK3CA

NM_006218.4:p.A53T

Associated Papers

Gene therapy targeting synaptopathy linked with Alzheimer's and Parkinson's disease.

Panda SP et al.

Neuroscience, 2026

Hemoglobin as a pseudoperoxidase and drug target for oxidative stress-related diseases.

Won W et al.

Signal Transduction and Targeted Therapy, 2025

40846833 (PubMed )
Supplement: 41392_2025_2366_MOESM1_ESM.docx

The Role of Astrocytes and Alpha-Synuclein in Parkinson's Disease: A Review.

Brash-Arias D et al.

Neurosci, 2024

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids.

Geurts MH et al.

Nature Communications, 2023

37591832 (PubMed )
Supplement: 41467_2023_40701_MOESM1_ESM.pdf

Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.

Padilla-Godínez FJ et al.

International Journal of Molecular Sciences, 2021

Role of lysosomes in physiological activities, diseases, and therapy.

Zhang Z et al.

Journal of Hematology & Oncology, 2021

Therapeutic Potential of Vital Transcription Factors in Alzheimer's and Parkinson's Disease With Particular Emphasis on Transcription Factor EB Mediated Autophagy.

Rai SN et al.

Frontiers in Neuroscience, 2021

Limelight on alpha-synuclein: pathological and mechanistic implications in neurodegeneration.

Wales P et al.

Journal of Parkinson's Disease, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."