Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.E76Q
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PIK3CA

NM_006218.4:p.E76Q

Associated Papers

Phenotypic and Functional Characterization of Oncohistone Mutations in Breast Cancers.

Edwards AD et al.

Biorxiv : the Preprint Server for Biology, 2025

High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing.

Kostecka A et al.

Npj Breast Cancer, 2022

35768433 (PubMed )
Supplement: 41523_2022_443_MOESM9_ESM.xlsx › DuplexSeq_all

Canine histiocytic sarcoma cell lines with SHP2 p.Glu76Gln or p.Glu76Ala mutations are sensitive to allosteric SHP2 inhibitor SHP099.

Tani H et al.

Veterinary and Comparative Oncology, 2020

The correlations of tumor mutational burden among single-region tissue, multi-region tissues and blood in non-small cell lung cancer.

Zhang Y et al.

Journal for Immunotherapy of Cancer, 2019

30944026 (PubMed )
Supplement: 40425_2019_581_MOESM3_ESM.pdf

Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition.

Chen L et al.

Leukemia, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."