Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.R88L
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PIK3CA

NM_006218.4:p.R88L

Associated Papers

Molecular insights into Profilin1-dependent regulation of cellular phosphatidylinositol-(4,5)-bisphosphate.

Orenberg A et al.

Biorxiv : the Preprint Server for Biology, 2025

Multisite gynecologic endometrioid adenocarcinomas: Can mutation profiling be used to distinguish synchronous primary cancers from metastases?

Barnes D et al.

Gynecologic Oncology Reports, 2022

Detailed analysis of phenotypes and genotypes in megalencephaly-capillary malformation-polymicrogyria syndrome caused by somatic mosaicism of PIK3CA mutations.

Park HJ et al.

Orphanet Journal of Rare Diseases, 2020

Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.

Ashktorab H et al.

Oncotarget, 2017

28002797 (PubMed )
Supplement: oncotarget-08-7852-s002.xlsx › PIK3CA.Ion

First-in-human phase I study of copanlisib (BAY 80-6946), an intravenous pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors and non-Hodgkin's lymphomas.

Patnaik A et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2016

27672108 (PubMed )
Supplement: supp_mdw282_mdw282supp.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."