Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.R115Q
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PIK3CA

NM_006218.4:p.R115Q

Associated Papers

Evolution and Co-occurrence of PI3K Pathway Gene Mutations in Endometrial Carcinoma Molecular Subtypes at the Single-Cell Level.

Da Cruz Paula A et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2025

Primary urethral adenocarcinoma harbors recurrent KRAS and EGFR alterations.

Zhao T et al.

Human Pathology, 2025

Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome.

Yavuz BR et al.

Npj Genomic Medicine, 2023

Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.

Gan M et al.

Cancer Medicine, 2022

35586877 (PubMed )
Supplement: CAM4-11-4070-s004.xlsx › Table_S1

High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing.

Kostecka A et al.

Npj Breast Cancer, 2022

35768433 (PubMed )
Supplement: 41523_2022_443_MOESM9_ESM.xlsx › DuplexSeq_all

The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers.

Rosen EY et al.

Nature Communications, 2022

35304457 (PubMed )
Supplement: 41467_2022_28848_MOESM1_ESM.pdf

Resistance to TRK inhibition mediated by convergent MAPK pathway activation.

Cocco E et al.

Nature Medicine, 2019

31406350 (PubMed )
Supplement: NIHMS1533563-supplement-1.xlsx › Patient_3

Comparative molecular profiling of HPV-induced squamous cell carcinomas.

Koncar RF et al.

Cancer Medicine, 2017

28556593 (PubMed )
Supplement: CAM4-6-1673-s004.xlsx › NGS

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.

Findlay JM et al.

Nature Communications, 2016

27045317 (PubMed )
Supplement: ncomms11111-s1.pdf

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response.

Lips EH et al.

Breast Cancer Research : Bcr, 2015

26433948 (PubMed )
Supplement: 13058_2015_642_MOESM4_ESM.xlsx › somatic_variants_proposal2.txt
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."