Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.F128I
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PIK3CA

NM_006218.4:p.F128I

Associated Papers

USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer.

Kumari N et al.

The Journal of Clinical Investigation, 2025

Elucidating PTEN conformational dynamics and phosphatase regulation via integrative modeling and mutation prediction.

Dawson JE et al.

Structure (london, England : 1993), 2025

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers.

Nakahata S et al.

Nature Communications, 2014

24569712 (PubMed )
Supplement: ncomms4393-s1.pdf
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