Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.K179M
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PIK3CA

NM_006218.4:p.K179M

Associated Papers

Next-Generation Sequencing Analysis of Mutations in Circulating Tumor DNA from the Plasma of Patients with Head-Neck Cancer Undergoing Chemo-Radiotherapy Using a Pan-Cancer Cell-Free Assay.

Koukourakis MI et al.

Current Oncology (toronto, Ont.), 2023

Insights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase model.

Oliver MD et al.

Bioscience Reports, 2017

Pten coordinates retinal neurogenesis by regulating Notch signalling.

Jo HS et al.

The Embo Journal, 2012

The proangiogenic phenotype of human tumor-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway.

Bussolati B et al.

Journal of Molecular Medicine (berlin, Germany), 2006

Akt activation by growth factors is a multiple-step process: the role of the PH domain.

Bellacosa A et al.

Oncogene, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."