Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.S405F
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PIK3CA

NM_006218.4:p.S405F

Associated Papers

Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC).

Richards CE et al.

International Journal of Molecular Sciences, 2023

37445722 (PubMed )
Supplement: ijms-24-10545-s001.zip › PTPN11_paper_supplementary_tables_25042023.pdf

Spatially interacting phosphorylation sites and mutations in cancer.

Huang KL et al.

Nature Communications, 2021

33875650 (PubMed )
Supplement: 41467_2021_22481_MOESM4_ESM.xlsx › TableS5.ActMutationClusters

The Gene Mutation Spectrum of Breast Cancer Analyzed by Semiconductor Sequencing Platform.

Liu Y et al.

Pathology Oncology Research : Por, 2020

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.

Chen L et al.

Nature Communications, 2018

Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations.

Jiang J et al.

Journal of Personalized Medicine, 2018

Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology.

Ibarrola-Villava M et al.

Oncotarget, 2016

26968814 (PubMed )
Supplement: oncotarget-07-22543-s001.pdf

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.

Kopetz S et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2015

26460303 (PubMed )
Supplement: supp_33.34.4032_DS_2015.632497.pdf

PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer.

Gonzalez-Angulo AM et al.

Molecular Cancer Therapeutics, 2011

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt
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