Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.E453A
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PIK3CA

NM_006218.4:p.E453A

Associated Papers

Molecular Basis of Oncogenic PI3K Proteins.

Sheng Z et al.

Cancers, 2024

PIK3CA and PIK3R1 tumor mutational landscape in a pan-cancer patient cohort and its association with pathway activation and treatment efficacy.

Tharin Z et al.

Scientific Reports, 2023

Detailed analysis of phenotypes and genotypes in megalencephaly-capillary malformation-polymicrogyria syndrome caused by somatic mosaicism of PIK3CA mutations.

Park HJ et al.

Orphanet Journal of Rare Diseases, 2020

Integrated Somatic and Germline Whole-Exome Sequencing Analysis in Women with Lung Cancer after a Previous Breast Cancer.

Coco S et al.

Cancers, 2019

30925779 (PubMed )
Supplement: cancers-11-00441-s001.zip › cancers-452240-Supplementary › Table_S3.xlsx › Table_S3

Cancer-Associated PIK3CA Mutations in Overgrowth Disorders.

Madsen RR et al.

Trends in Molecular Medicine, 2018

30197175 (PubMed )
Supplement: mmc1.pdf

PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer.

Urick ME et al.

Cancer Research, 2011

A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas.

Rudd ML et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."