Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.L455del1
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PIK3CA

NM_006218.4:p.L455del1

Associated Papers

Functional characterization of PI3K C2 domain mutations detected in breast cancer circulating tumor cells and metastatic cells.

Smit DJ et al.

Cellular Signalling, 2024

PIK3CA C2 Domain Deletions Hyperactivate Phosphoinositide 3-kinase (PI3K), Generate Oncogene Dependence, and Are Exquisitely Sensitive to PI3Kα Inhibitors.

Croessmann S et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."