Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.K802R
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PIK3CA

NM_006218.4:p.K802R

Associated Papers

Insights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase model.

Oliver MD et al.

Bioscience Reports, 2017

Yeast-based methods to assess PTEN phosphoinositide phosphatase activity in vivo.

Rodríguez-Escudero I et al.

Methods (san Diego, Calif.), 2015

Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha.

Zunder ER et al.

Cancer Cell, 2008

Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.

Rodríguez-Escudero I et al.

The Biochemical Journal, 2005

Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha ). Functions of lipid kinase-deficient PI3Kalpha in signaling.

Pirola L et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."