Associated Papers
Novel role for PI3Kβ in placental function through regulation of system A amino acid transporter expression, associated with embryonic lethality.
Conduit SE et al.
Cellular and Molecular Life Sciences : Cmls, 2025
RGS20 Promotes Tumor Progression through Modulating PI3K/AKT Signaling Activation in Penile Cancer.
Shi D et al.
Journal of Oncology, 2022
The role of the PIK3CA gene in the development and aging of the brain.
Xie S et al.
Scientific Reports, 2021
Class I Phosphoinositide 3-Kinase PIK3CA/p110α and PIK3CB/p110β Isoforms in Endometrial Cancer.
Mazloumi Gavgani F et al.
International Journal of Molecular Sciences, 2018
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer.
Hao Y et al.
Nature Communications, 2016
Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.
Guillermet-Guibert J et al.
Plos Genetics, 2015
Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish.
Choorapoikayil S et al.
Disease Models & Mechanisms, 2013
Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism.
Foukas LC et al.
Embo Molecular Medicine, 2013
Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.
Dubois E et al.
Cellular Signalling, 2012
Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor.
Berenjeno IM et al.
The Biochemical Journal, 2012
The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.
Ramadani F et al.
Science Signaling, 2010
Comparing the roles of the p110α and p110β isoforms of PI3K in signaling and cancer.
Ilić N et al.
Current Topics in Microbiology and Immunology, 2010
Should individual PI3 kinase isoforms be targeted in cancer?
Jia S et al.
Current Opinion in Cell Biology, 2009
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.
Graupera M et al.
Nature, 2008
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.
Foukas LC et al.
Nature, 2006
Cloning and mutagenesis of the p110 alpha subunit of human phosphoinositide 3'-hydroxykinase.
Stirdivant SM et al.
Bioorganic & Medicinal Chemistry, 1997