Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.A1046T
Back to variants list

PIK3CA

NM_006218.4:p.A1046T

Associated Papers

Targeted next-generation sequencing of 491 lung cancers in clinical practice: Implications for future detection strategy and targeted therapy.

Liu XD et al.

Heliyon, 2024

38496837 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Mutant PIK3CA is a targetable driver alteration in histiocytic neoplasms.

Durham BH et al.

Blood Advances, 2023

Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia.

Pilheden M et al.

Hemasphere, 2022

36204688 (PubMed )
Supplement: hs9-6-e785-s001.xlsx › S6_Cancer-associated_mutations

Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis.

Hoefflin R et al.

Cancers, 2021

33800365 (PubMed )
Supplement: cancers-13-01151-s001.zip › Supplementary_Data_1.xlsx › S_Data_1

Clinical Implication of Concordant or Discordant Genomic Profiling between Primary and Matched Metastatic Tissues in Patients with Colorectal Cancer.

Choi JY et al.

Cancer Research and Treatment, 2020

High Proportion of Potential Candidates for Immunotherapy in a Chilean Cohort of Gastric Cancer Patients: Results of the FORCE1 Study.

Cordova-Delgado M et al.

Cancers, 2019

31480291 (PubMed )
Supplement: cancers-11-01275-s001.zip › Supplementary_data_file_1.xlsx › DNA

Targeted next-generation sequencing of cancer-related genes in thyroid carcinoma: A single institution's experience.

Bandoh N et al.

Oncology Letters, 2018

PTPRT and PTPRD Deleterious Mutations and Deletion Predict Bevacizumab Resistance in Metastatic Colorectal Cancer Patients.

Hsu HC et al.

Cancers, 2018

30200630 (PubMed )
Supplement: cancers-10-00314-s001.zip › cancers-335170-sup › Supplementary_Table_S2.xlsx › Supplementary_Table_2

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.

Chen L et al.

Nature Communications, 2018

Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies.

Alvi MA et al.

British Journal of Cancer, 2017

28595259 (PubMed )
Supplement: bjc2017168x11.xlsx › Supplementary_table_4

Rosai-Dorfman Disease Harboring an Activating KRAS K117N Missense Mutation.

Shanmugam V et al.

Head and Neck Pathology, 2016

Contribution of Beta-HPV Infection and UV Damage to Rapid-Onset Cutaneous Squamous Cell Carcinoma during BRAF-Inhibition Therapy.

Cohen DN et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.

Wong SQ et al.

British Journal of Cancer, 2015

25742471 (PubMed )
Supplement: bjc201580x7.xls › Supp_Table_3

Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease.

Emile JF et al.

Blood, 2014

Complex interactions between the components of the PI3K/AKT/mTOR pathway, and with components of MAPK, JAK/STAT and Notch-1 pathways, indicate their involvement in meningioma development.

El-Habr EA et al.

Virchows Archiv : an International Journal of Pathology, 2014

Prognostic role of PIK3CA mutation in colorectal cancer: cohort study and literature review.

Liao X et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2012

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.

Nosho K et al.

Neoplasia (new York, N.y.), 2008

Histomolecular characterization of intracranial meningiomas developed in patients exposed to high-dose cyproterone acetate: an antiandrogen treatment.

Portet S et al.

Neuro-oncology Advances, 0

32642646 (PubMed )
Supplement: vdz003_suppl_supplementary_table_1.xlsx › Feuil1
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."