Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CA
Variant:p.H1048L
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PIK3CA

NM_006218.4:p.H1048L

Associated Papers

Mosaic hotspot PIK3CA mutations cause non-cell-autonomous vascular overgrowth and pan-lineage dysregulation at disease onset.

Brunsdon H et al.

Biorxiv : the Preprint Server for Biology, 2025

Large-scale genomic sequencing reveals adaptive opportunity of targeting mutated-PI3Kα in early and advanced HER2-positive breast cancer.

Guo LW et al.

Clinical and Translational Medicine, 2021

Mutational Landscape of PI3K-AKT-mTOR Pathway in Breast Cancer: Implications for Targeted Therapeutics.

Xiao W et al.

Journal of Cancer, 2021

Response to mTOR and PI3K inhibitors in enzalutamide-resistant luminal androgen receptor triple-negative breast cancer patient-derived xenografts.

Coussy F et al.

Theranostics, 2020

Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.

Chen L et al.

Nature Communications, 2018

29636477 (PubMed )
Supplement: 41467_2018_3867_MOESM1_ESM.pdf

Ultra-deep targeted sequencing of advanced oral squamous cell carcinoma identifies a mutation-based prognostic gene signature.

Chen SJ et al.

Oncotarget, 2015

25980437 (PubMed )
Supplement: oncotarget-06-18066-s004.xlsx › Sheet1

Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.

Beaufort CM et al.

Plos One, 2014

25230021 (PubMed )
Supplement: pone.0103988.s007.xlsx › paper_mutation_table

PIK3CA exon 20 mutation is independently associated with a poor prognosis in breast cancer patients.

Lai YL et al.

Annals of Surgical Oncology, 2008

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