Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CB
Variant:p.D1067Y
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PIK3CB

NM_006219.3:p.D1067Y

Associated Papers

A phase I study of AZD8186 in combination with docetaxel in patients with PTEN-mutated or PIK3CB-mutated advanced solid tumors.

Schram AM et al.

Esmo Open, 2025

P16 immunohistochemistry is a sensitive and specific surrogate marker for CDKN2A homozygous deletion in gliomas.

Vij M et al.

Acta Neuropathologica Communications, 2023

37138345 (PubMed )
Supplement: 40478_2023_1573_MOESM1_ESM.xlsx › Data1

N6-methyladenosine mRNA methylation of PIK3CB regulates AKT signalling to promote PTEN-deficient pancreatic cancer progression.

Tian J et al.

Gut, 2020

Class I Phosphoinositide 3-Kinase PIK3CA/p110α and PIK3CB/p110β Isoforms in Endometrial Cancer.

Mazloumi Gavgani F et al.

International Journal of Molecular Sciences, 2018

The Role of Class IA Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunits in Glioblastoma.

Pridham KJ et al.

Frontiers in Oncology, 2017

Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β.

Nakanishi Y et al.

Cancer Research, 2016

Functional characterization of a novel somatic oncogenic mutation of PIK3CB.

Whale AD et al.

Signal Transduction and Targeted Therapy, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."