Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CB
Variant:p.K805R
Back to variants list

PIK3CB

NM_006219.3:p.K805R

Associated Papers

Novel role for PI3Kβ in placental function through regulation of system A amino acid transporter expression, associated with embryonic lethality.

Conduit SE et al.

Cellular and Molecular Life Sciences : Cmls, 2025

PTEN Loss Promotes PI3Kβ Phosphorylation and EPHA2/SRC/p-PI3KβY962 Complex Assembly to Drive Tumorigenesis.

Tang S et al.

Cancer Discovery, 2025

E-cadherin downregulation sensitizes PTEN-mutant tumors to PI3Kβ silencing.

Millán-Uclés Á et al.

Oncotarget, 2016

Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β.

Nakanishi Y et al.

Cancer Research, 2016

Phosphoinositide 3-kinase beta controls replication factor C assembly and function.

Redondo-Muñoz J et al.

Nucleic Acids Research, 2013

Comparing the roles of the p110α and p110β isoforms of PI3K in signaling and cancer.

Ilić N et al.

Current Topics in Microbiology and Immunology, 2010

Should individual PI3 kinase isoforms be targeted in cancer?

Jia S et al.

Current Opinion in Cell Biology, 2009

Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development.

Ciraolo E et al.

Science Signaling, 2008

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."