Varaico: Literature-Extracted Genetic Variants

Gene:PIK3CG
Variant:p.N1085S
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PIK3CG

NM_001282426.2:p.N1085S

Associated Papers

Hyperactivation of the PI3K pathway in inborn errors of immunity: current understanding and therapeutic perspectives.

IJspeert H et al.

Immunotherapy Advances, 2024

The role of PI3Kγ in the immune system: new insights and translational implications.

Lanahan SM et al.

Nature Reviews. Immunology, 2022

Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors.

Rathinaswamy MK et al.

Elife, 2021

Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation.

Thian M et al.

Haematologica, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."