Associated Papers
Cancer-Associated PIK3R1 Genetic Aberrations and Precision Medicine.
Xie H et al.
International Journal of Medical Sciences, 2025
A novel mutant PIK3R1EY451delinsD breast cancer patient resistant to HER2-targeted therapy treated with everolimus: a case report.
Wang K et al.
Molecular Biology Reports, 2022
Genomic alterations in breast cancer: level of evidence for actionability according to ESMO Scale for Clinical Actionability of molecular Targets (ESCAT).
Condorelli R et al.
Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2019
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients.
Chen L et al.
Nature Communications, 2018
PIKing the type and pattern of PI3K pathway mutations in endometrioid endometrial carcinomas.
Marchiò C et al.
Gynecologic Oncology, 2015
Signalling: uncovering new functions of PI3K mutations.
Seton-Rogers S
Nature Reviews. Cancer, 2014
Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.
Cheung LW et al.
Cancer Cell, 2014
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