Varaico: Literature-Extracted Genetic Variants

Gene:PIK3R1
Variant:p.L380del1
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PIK3R1

NM_181523.3:p.L380del1

Associated Papers

Cancer-Associated PIK3R1 Genetic Aberrations and Precision Medicine.

Xie H et al.

International Journal of Medical Sciences, 2025

A Novel Type of IDH-wildtype Glioma Characterized by Gliomatosis Cerebri-like Growth Pattern, TERT Promoter Mutation, and Distinct Epigenetic Profile.

Muench A et al.

The American Journal of Surgical Pathology, 2023

Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.

Sakthikumar S et al.

Veterinary and Comparative Oncology, 2023

37248814 (PubMed )
Supplement: supplement_1.xlsx › Suppl._Table_6

Clinical Application of Comprehensive Genomic Profiling Tests for Diffuse Gliomas.

Omura T et al.

Cancers, 2022

35626060 (PubMed )
Supplement: cancers-14-02454-s001.zip › cancers-1674301-SI.xlsx › gene_aberrations

Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases.

Li X et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

Sclerosing Polycystic "Adenosis" of Salivary Glands: A Neoplasm Characterized by PI3K Pathway Alterations More Correctly Named Sclerosing Polycystic Adenoma.

Bishop JA et al.

Head and Neck Pathology, 2020

Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches.

Ellis HP et al.

Journal of Oncology, 2019

32082376 (PubMed )
Supplement: 4878547.f1.zip › 4878547.f1 › Ellis_et_al_SNVs_041018_Supplementary_Tables.xlsx › TableS7_TCGA_mutatons

TERT promoter wild-type glioblastomas show distinct clinical features and frequent PI3K pathway mutations.

Williams EA et al.

Acta Neuropathologica Communications, 2018

30333046 (PubMed )
Supplement: 40478_2018_613_MOESM3_ESM.xlsx › Sheet1

Next generation sequencing of the nidus of early (adenosquamous proliferation rich) radial sclerosing lesions of the breast reveals evidence for a neoplastic precursor lesion.

Wilsher MJ et al.

The Journal of Pathology. Clinical Research, 2017

Infiltrating epitheliosis of the breast: characterization of histological features, immunophenotype and genomic profile.

Eberle CA et al.

Histopathology, 2016

Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology.

Weisman PS et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2016

26939876 (PubMed )
Supplement: NIHMS752475-supplement-3.xlsx › Supplementary_Table_3

PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients.

Draaisma K et al.

Acta Neuropathologica Communications, 2015

26699864 (PubMed )
Supplement: 40478_2015_265_MOESM1_ESM.xlsx › Suplementary_table_3

Longitudinal profiling of IDH-mutant astrocytomas reveals acquired RAS-MAPK pathway mutations associated with inferior survival.

Rodriguez Almaraz E et al.

Neuro-oncology Advances, 0

40051658 (PubMed )
Supplement: vdaf024_suppl_supplementary_tables_s1-s4.xlsx › Table_S2
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