Varaico: Literature-Extracted Genetic Variants

Gene:PIK3R1
Variant:p.L449del1
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PIK3R1

NM_181523.3:p.L449del1

Associated Papers

Evolution and Co-occurrence of PI3K Pathway Gene Mutations in Endometrial Carcinoma Molecular Subtypes at the Single-Cell Level.

Da Cruz Paula A et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2025

PIK3R1 underexpression is an independent prognostic marker in breast cancer.

Cizkova M et al.

Bmc Cancer, 2013

24229379 (PubMed )
Supplement: 1471-2407-13-545-S3.pdf

High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability.

Cheung LW et al.

Cancer Discovery, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."