Varaico: Literature-Extracted Genetic Variants

Gene:PIK3R1
Variant:p.K459del1
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PIK3R1

NM_181523.3:p.K459del1

Associated Papers

Long-read sequencing of an advanced cancer cohort resolves rearrangements, unravels haplotypes, and reveals methylation landscapes.

O'Neill K et al.

Cell Genomics, 2024

Recurrent oligodendroglioma with changed 1p/19q status.

Barresi V et al.

Neuropathology : Official Journal of the Japanese Society of Neuropathology, 2022

35144313 (PubMed )
Supplement: NEUP-42-160-s001.xlsx › Foglio1

Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy.

Zhang Y et al.

Cell Reports, 2021

34788622 (PubMed )
Supplement: NIHMS1757901-supplement-2.xlsx › SNVs_indels

Mutations of the MAPK/TSC/mTOR pathway characterize periventricular glioblastoma with epithelioid SEGA-like morphology-morphological and therapeutic implications.

Georgescu MM et al.

Oncotarget, 2019

Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.

Hirshfield KM et al.

The Oncologist, 2016

27566247 (PubMed )
Supplement: supp_the2016-0049_Supplemental_Tables.pdf

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nik-Zainal S et al.

Nature, 2016

27135926 (PubMed )
Supplement: NIHMS68344-supplement-Supplementary_Tables_1-21.zip › nature17676-s3 › Supplementary_Table_14.Driver.Events.By.Mutation.Type.01052015.v2.xlsx › Subs.indels

PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer.

Urick ME et al.

Cancer Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."