Varaico: Literature-Extracted Genetic Variants

Gene:PINK1
Variant:p.V87_C92delFs
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PINK1

NM_032409.3:p.V87_C92delFs

Associated Papers

A LON-ClpP Proteolytic Axis Degrades Complex I to Extinguish ROS Production in Depolarized Mitochondria.

Pryde KR et al.

Cell Reports, 2016

27926857 (PubMed )
Supplement: mmc1.pdf

Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson's disease.

Celardo I et al.

Cell Death & Disease, 2016

PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy.

Pryde KR et al.

The Journal of Cell Biology, 2016

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