Varaico: Literature-Extracted Genetic Variants

Gene:PINK1
Variant:p.T257A
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PINK1

NM_032409.3:p.T257A

Associated Papers

Structural Mechanisms of Mitochondrial Quality Control Mediated by PINK1 and Parkin.

Trempe JF et al.

Journal of Molecular Biology, 2023

PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402.

Aerts L et al.

The Journal of Biological Chemistry, 2015

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.

Kondapalli C et al.

Open Biology, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."