Associated Papers
PPAR-gamma agonist pioglitazone recovers mitochondrial quality control in fibroblasts from PITRM1-deficient patients.
Di Donfrancesco A et al.
Frontiers in Pharmacology, 2023
In-frame deletion in canine PITRM1 is associated with a severe early-onset epilepsy, mitochondrial dysfunction and neurodegeneration.
Hytönen MK et al.
Human Genetics, 2021
Role of PITRM1 in Mitochondrial Dysfunction and Neurodegeneration.
Brunetti D et al.
Biomedicines, 2021
Gain of PITRM1 peptidase in cortical neurons affords protection of mitochondrial and synaptic function in an advanced age mouse model of Alzheimer's disease.
Du F et al.
Aging Cell, 2021
The Power of Yeast in Modelling Human Nuclear Mutations Associated with Mitochondrial Diseases.
Ceccatelli Berti C et al.
Genes, 2021
Functional coupling of presequence processing and degradation in human mitochondria.
Kücükköse C et al.
The Febs Journal, 2021
Mitochondrial PITRM1 peptidase loss-of-function in childhood cerebellar atrophy.
Langer Y et al.
Journal of Medical Genetics, 2018
Functional requirement for human pitrilysin metallopeptidase 1 arginine 183, mutated in amyloidogenic neuropathy.
Smith-Carpenter JE et al.
Protein Science : a Publication of the Protein Society, 2018
Defective PITRM1 mitochondrial peptidase is associated with Aβ amyloidotic neurodegeneration.
Brunetti D et al.
Embo Molecular Medicine, 2016
Amyloid-β in mitochondrial disease: mutation in a human metallopeptidase links amyloidotic neurodegeneration with mitochondrial processing.
Boczonadi V et al.
Embo Molecular Medicine, 2016
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