Associated Papers
The diverse effects of pathogenic point mutations on ion channel activity of a gain-of-function polycystin-2.
Wang Y et al.
The Journal of Biological Chemistry, 2023
Structure and function of polycystin channels in primary cilia.
Ta CM et al.
Cellular Signalling, 2020
Molecular dysregulation of ciliary polycystin-2 channels caused by variants in the TOP domain.
Vien TN et al.
Proceedings of the National Academy of Sciences of the United States of America, 2020
Extracellular Loops Are Essential for the Assembly and Function of Polycystin Receptor-Ion Channel Complexes.
Salehi-Najafabadi Z et al.
The Journal of Biological Chemistry, 2017
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).
Grieben M et al.
Nature Structural & Molecular Biology, 2017
Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutant.
Arif Pavel M et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016
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