Associated Papers
Role of PKD2 in the endoplasmic reticulum calcium homeostasis.
Liu X et al.
Frontiers in Physiology, 2022
Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis.
Park JE et al.
Nature Communications, 2019
Structure and function of polycystins: insights into polycystic kidney disease.
Douguet D et al.
Nature Reviews. Nephrology, 2019
Vasopressin and disruption of calcium signalling in polycystic kidney disease.
Chebib FT et al.
Nature Reviews. Nephrology, 2015
Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.
Streets AJ et al.
Human Molecular Genetics, 2013
Aurora A kinase activity influences calcium signaling in kidney cells.
Plotnikova OV et al.
The Journal of Cell Biology, 2011
Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2.
Molland KL et al.
The Biochemical Journal, 2010
A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes.
Giamarchi A et al.
The Embo Journal, 2010
Polycystin-1 C-terminal cleavage is modulated by polycystin-2 expression.
Bertuccio CA et al.
The Journal of Biological Chemistry, 2009
Function and regulation of TRPP2 at the plasma membrane.
Tsiokas L
American Journal of Physiology. Renal Physiology, 2009
Nek8 regulates the expression and localization of polycystin-1 and polycystin-2.
Sohara E et al.
Journal of the American Society of Nephrology : Jasn, 2008
Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2.
Li X et al.
Nature Cell Biology, 2005
Polycystins: polymodal receptor/ion-channel cellular sensors.
Delmas P
Pflugers Archiv : European Journal of Physiology, 2005
Cellular and molecular function of mucolipins (TRPML) and polycystin 2 (TRPP2).
Qian F et al.
Pflugers Archiv : European Journal of Physiology, 2005
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.
Köttgen M et al.
The Embo Journal, 2005
Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.
Cai Y et al.
The Journal of Biological Chemistry, 2004