Associated Papers
Biphosphoglycerate Mutase: A Novel Therapeutic Target for Malaria?
Azzuolo A et al.
Transfusion Medicine Reviews, 2023
Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment.
Navarro S et al.
Molecular Therapy. Methods & Clinical Development, 2021
Prevalence of pyruvate kinase deficiency: A systematic literature review.
Secrest MH et al.
European Journal of Haematology, 2020
Pyruvate Kinase and Fcγ Receptor Gene Copy Numbers Associated With Malaria Phenotypes.
Faik I et al.
The Journal of Infectious Diseases, 2017
The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.
Laroque A et al.
Plos One, 2017
Safe and Efficient Gene Therapy for Pyruvate Kinase Deficiency.
Garcia-Gomez M et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy, 2016
Modulation of Malaria Phenotypes by Pyruvate Kinase (PKLR) Variants in a Thai Population.
van Bruggen R et al.
Plos One, 2015
N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium.
Richer E et al.
Journal of Immunology (baltimore, Md. : 1950), 2010
Mapping of Char10, a novel malaria susceptibility locus on mouse chromosome 9.
Min-Oo G et al.
Genes and Immunity, 2010
Analysis of malaria associated genetic traits in Cabo Verde, a melting pot of European and sub Saharan settlers.
Alves J et al.
Blood Cells, Molecules & Diseases, 2010
Fifteen novel mutations in PKLR associated with pyruvate kinase (PK) deficiency: structural implications of amino acid substitutions in PK.
van Wijk R et al.
Human Mutation, 2009
Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus.
Min-Oo G et al.
The Journal of Experimental Medicine, 2007
Pyruvate kinase deficiency in mice protects against malaria.
Min-Oo G et al.
Nature Genetics, 2003
Pyruvate kinase deficiency: correlation between enzyme activity, extent of hemolytic anemia and protection against malaria in independent mouse mutants.
Min-Oo G et al.
Blood Cells, Molecules & Diseases, 0
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