Associated Papers
Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
Nandi S et al.
The Journal of Biological Chemistry, 2020
Cancer-associated mutations in human pyruvate kinase M2 impair enzyme activity.
Liu VM et al.
Febs Letters, 2020
Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells.
Xia L et al.
Oncotarget, 2017
Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association.
Yang YC et al.
Oncogene, 2016
Pyruvate kinase: Function, regulation and role in cancer.
Israelsen WJ et al.
Seminars in Cell & Developmental Biology, 2015
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