Varaico: Literature-Extracted Genetic Variants

Gene:PKN1
Variant:p.K644E
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PKN1

NM_002741.5:p.K644E

Associated Papers

PKN1 promotes synapse maturation by inhibiting mGluR-dependent silencing through neuronal glutamate transporter activation.

Yasuda H et al.

Communications Biology, 2020

PKN1 kinase-negative knock-in mice develop splenomegaly and leukopenia at advanced age without obvious autoimmune-like phenotypes.

Siddique SM et al.

Scientific Reports, 2019

Negative regulation of constitutive NF-kappaB and JNK signaling by PKN1-mediated phosphorylation of TRAF1.

Kato T et al.

Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."