Varaico: Literature-Extracted Genetic Variants

Gene:PLA2G7
Variant:p.Q281R
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PLA2G7

NM_005084.4:p.Q281R

Associated Papers

Impact of a non-synonymous Q281R polymorphism on structure of human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2 ).

Gurung AB et al.

Journal of Cellular Biochemistry, 2018

Association between Ala379Val polymorphism of lipoprotein-associated phospholipase A2 and migraine without aura in Iranian population.

Haghdoost F et al.

Iranian Journal of Neurology, 2016

The prevalence of platelet activating factor acetylhydrolase single nucleotide polymorphisms in relationship to necrotizing enterocolitis in Northwest Louisiana infants.

Sankararaman S et al.

Springerplus, 2013

Functional Consequences of Mutations and Polymorphisms in the Coding Region of the PAF Acetylhydrolase (PAF-AH) Gene.

Stafforini DM

Pharmaceuticals (basel, Switzerland), 2009

Inter-individual variability of plasma PAF-acetylhydrolase activity in ARDS patients and PAFAH genotype.

Li S et al.

Journal of Clinical Pharmacy and Therapeutics, 2009

Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.

Ryu GM et al.

Nucleic Acids Research, 2009

19139070 (PubMed )
Supplement: gkn1008_nar-01723-s-2008-File009.xls › TypeII_

Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis.

Samanta U et al.

The Journal of Biological Chemistry, 2008

Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients.

Ishihara M et al.

Journal of Human Genetics, 2004

The PON1 M55L gene polymorphism is associated with reduced HDL-associated PAF-AH activity.

Kakafika AI et al.

Journal of Lipid Research, 2003

The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma.

Kruse S et al.

American Journal of Human Genetics, 2000

Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma.

Stafforini DM et al.

The Journal of Clinical Investigation, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."