Varaico: Literature-Extracted Genetic Variants

Gene:PLA2G7
Variant:p.R92H
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PLA2G7

NM_005084.4:p.R92H

Associated Papers

Association Between Genetic Polymorphisms in the Prostaglandin Pathway and the Development of Patent Ductus Arteriosus in Preterm Infants.

Minta M et al.

International Journal of Molecular Sciences, 2025

Unveiling the Synergy of Serum Lipoprotein-Associated Phospholipase A2 and PLA2G7 Gene Polymorphism (rs1805017) as Key Determinants of Coronary Artery Disease Risk and Severity: Implications for Early Intervention.

Luqman H et al.

Cureus, 2024

Association Lp-PLA2 Gene Polymorphisms with Coronary Heart Disease.

Ma S et al.

Disease Markers, 2022

Case report: Whole-exome sequencing identifies a novel DES mutation (p. E434K) in a Chinese family with cardiomyopathy and sudden cardiac death.

Liu YX et al.

Frontiers in Cardiovascular Medicine, 2022

36277747 (PubMed )
Supplement: Data_Sheet_1.xls › Data_Sheet_1

Case report: Two unique nonsense mutations in HTRA1-related cerebral small vessel disease in a Chinese population and literature review.

Chen W et al.

Frontiers in Neurology, 2022

36619910 (PubMed )
Supplement: Data_Sheet_3.ZIP › case-C › 3.________ › CA2245B________.__________________________________.xlsx › sheet1

Association of the G994T and R92H genotypes of platelet-activating factor acetylhydrolase with risk of preeclampsia in Chinese women.

Zhou M et al.

Pregnancy Hypertension, 2020

Association of SOD2 A16V and PON2 S311C polymorphisms with polycystic ovary syndrome in Chinese women.

Liu Q et al.

Journal of Endocrinological Investigation, 2019

Evolutionary history of human colitis-associated colorectal cancer.

Baker AM et al.

Gut, 2019

29991641 (PubMed )
Supplement: gutjnl-2018-316191supp003.xlsx › Supp_Table_5_-_mutations

Impact of a non-synonymous Q281R polymorphism on structure of human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2 ).

Gurung AB et al.

Journal of Cellular Biochemistry, 2018

Interaction between nonsynonymous polymorphisms in PLA2G7 gene and smoking on the risk of coronary heart disease in a Chinese population.

Chi Y et al.

Journal of Thrombosis and Thrombolysis, 2018

Correlations Between LP-PLA2 Gene Polymorphisms and Susceptibility and Severity of Acute Pancreatitis in a Chinese Population.

Ma M et al.

Genetic Testing and Molecular Biomarkers, 2017

Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib.

Yeo A et al.

Plos One, 2017

Associations between four types of single-nucleotide polymorphisms in PLA2G7 gene and clinical atherosclerosis: a meta-analysis.

Santoso A et al.

American Journal of Cardiovascular Disease, 2017

A previously unreported impact of a PLA2G7 gene polymorphism on the plasma levels of lipoprotein-associated phospholipase A2 activity and mass.

Qi Y et al.

Scientific Reports, 2016

Association between Ala379Val polymorphism of lipoprotein-associated phospholipase A2 and migraine without aura in Iranian population.

Haghdoost F et al.

Iranian Journal of Neurology, 2016

Associations of platelet-activating factor acetylhydrolase gene polymorphisms with risk of ischemic stroke.

Ma Y

Biomedical Reports, 2016

Nonsynonymous polymorphisms in PLA2G7 gene are associated with the risk of coronary heart disease in a southern Chinese population.

Hong M et al.

Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2015

Association between polymorphisms in phospholipase A2 genes and the plasma triglyceride response to an n-3 PUFA supplementation: a clinical trial.

Tremblay BL et al.

Lipids in Health and Disease, 2015

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-A8-A06O-01A.domain

Associations of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms with circulating PAF-AH levels and risk of coronary heart disease or blood stasis syndrome in the Chinese Han population.

Zheng GH et al.

Molecular Biology Reports, 2014

The prevalence of platelet activating factor acetylhydrolase single nucleotide polymorphisms in relationship to necrotizing enterocolitis in Northwest Louisiana infants.

Sankararaman S et al.

Springerplus, 2013

An association study between genetic polymorphisms related to lipoprotein-associated phospholipase A(2) and coronary heart disease.

Xu L et al.

Experimental and Therapeutic Medicine, 2013

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.

Grallert H et al.

European Heart Journal, 2012

PLA2G7 gene polymorphisms and coronary heart disease risk: a meta-analysis.

Wang Q et al.

Thrombosis Research, 2010

PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.

Casas JP et al.

Circulation, 2010

Genetic deficiency of plasma lipoprotein-associated phospholipase A2 (PLA2G7 V297F null mutation) and risk of Alzheimer's disease in Japan.

Koshy B et al.

Journal of Alzheimer's Disease : Jad, 2010

Association of PLA2G7 polymorphisms with carotid atherosclerosis in hypertensive Japanese.

Miwa Y et al.

Hypertension Research : Official Journal of the Japanese Society of Hypertension, 2009

Functional Consequences of Mutations and Polymorphisms in the Coding Region of the PAF Acetylhydrolase (PAF-AH) Gene.

Stafforini DM

Pharmaceuticals (basel, Switzerland), 2009

Inter-individual variability of plasma PAF-acetylhydrolase activity in ARDS patients and PAFAH genotype.

Li S et al.

Journal of Clinical Pharmacy and Therapeutics, 2009

Associations of PLA2G7 gene polymorphisms with plasma lipoprotein-associated phospholipase A2 activity and coronary heart disease in a Chinese Han population: the Beijing atherosclerosis study.

Hou L et al.

Human Genetics, 2009

Genetic variants and haplotypes of lipoprotein associated phospholipase A2 and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study).

Hoffmann MM et al.

Journal of Thrombosis and Haemostasis : Jth, 2009

Crystal structure of human plasma platelet-activating factor acetylhydrolase: structural implication to lipoprotein binding and catalysis.

Samanta U et al.

The Journal of Biological Chemistry, 2008

Identification of candidate genes for human retinal degeneration loci using differentially expressed genes from mouse photoreceptor dystrophy models.

Demos C et al.

Molecular Vision, 2008

Identification of a domain that mediates association of platelet-activating factor acetylhydrolase with high density lipoprotein.

Gardner AA et al.

The Journal of Biological Chemistry, 2008

Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets.

Sutton BS et al.

Human Molecular Genetics, 2008

Platelet activating factor-acetylhydrolase (PAF-AH) activity and HDL levels, but not PAF-AH gene polymorphisms, are associated with successful aging in Sicilian octogenarians.

Campo S et al.

Aging Clinical and Experimental Research, 2008

Two new highly polymorphic markers in the 3' UTR region of the PLA2G7 gene.

Gomez Lira M et al.

International Journal of Immunogenetics, 2007

Association of sixty-one non-synonymous polymorphisms in forty-one hypertension candidate genes with blood pressure variation and hypertension.

Kokubo Y et al.

Hypertension Research : Official Journal of the Japanese Society of Hypertension, 2006

Platelet-activating factor-acetylhydrolase and PAF-receptor gene haplotypes in relation to future cardiovascular event in patients with coronary artery disease.

Ninio E et al.

Human Molecular Genetics, 2004

The Ile198Thr and Ala379Val variants of plasmatic PAF-acetylhydrolase impair catalytical activities and are associated with atopy and asthma.

Kruse S et al.

American Journal of Human Genetics, 2000

Lipoprotein-associated phospholipase A2 mass and activity in children with heterozygous familial hypercholesterolemia and unaffected siblings: effect of pravastatin.

Ryu SK et al.

Journal of Clinical Lipidology, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."