Varaico: Literature-Extracted Genetic Variants

Gene:PLCB3
Variant:p.S845L
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PLCB3

NM_000932.5:p.S845L

Associated Papers

Tumor evolution and immune microenvironment dynamics in primary and relapsed mantle cell lymphoma.

Wan H et al.

Cell Reports. Medicine, 2025

40876452 (PubMed )
Supplement: mmc2.xlsx › TableS3._Nonsilent_mutations

From CFTR to a CF signalling network: a systems biology approach to study Cystic Fibrosis.

Najm M et al.

Bmc Genomics, 2024

Update on Calcium Signaling in Cystic Fibrosis Lung Disease.

Rimessi A et al.

Frontiers in Pharmacology, 2021

Phospholipase C families: Common themes and versatility in physiology and pathology.

Katan M et al.

Progress in Lipid Research, 2020

Rare Tumor-Normal Matched Whole Exome Sequencing Identifies Novel Genomic Pathogenic Germline and Somatic Aberrations.

Sprissler R et al.

Cancers, 2020

32570879 (PubMed )
Supplement: cancers-12-01618-s001.zip › cancers-817200-Supplementary_Materials3 › Supplementary_table_S1.xlsx › TSG

Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis.

Cabrini G et al.

Frontiers in Immunology, 2020

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.

Justice AE et al.

Nature Genetics, 2019

30778226 (PubMed )
Supplement: NIHMS1016010-supplement-SupplementaryData16.xlsx › SD16._Locus_Lookups

PLCB3 Loss of Function Reduces Pseudomonas aeruginosa-Dependent IL-8 Release in Cystic Fibrosis.

Rimessi A et al.

American Journal of Respiratory Cell and Molecular Biology, 2018

Phospholipase C-β3 is a key modulator of IL-8 expression in cystic fibrosis bronchial epithelial cells.

Bezzerri V et al.

Journal of Immunology (baltimore, Md. : 1950), 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."