Associated Papers
Hyperactive PLCG1 induces cell-autonomous and bystander T cell activation and drug resistance.
Zeng L et al.
Embo Reports, 2025
Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function.
Ma M et al.
Elife, 2025
Phosphoinositide-specific phospholipase C enzymes: Recent advances in a long journey.
Macrae C et al.
Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids, 2025
Heterozygous variants in PLCG1 affect hearing, vision, cardiac, and immune function.
Ma M et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Single Cell Resolution Tracking of Cutaneous T-Cell Lymphoma Reveals Clonal Evolution in Disease Progression.
Dorando HK et al.
Biorxiv : the Preprint Server for Biology, 2025
Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations.
Myers CS et al.
Haematologica, 2024
GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway.
Ikeuchi H et al.
Oncogene, 2024
TCR Pathway Mutations in Mature T Cell Lymphomas.
Zhang Y et al.
Journal of Immunology (baltimore, Md. : 1950), 2023
TP53 mutations identify high-risk events for peripheral T-cell lymphoma treated with CHOP-based chemotherapy.
Johnson WT et al.
Blood Advances, 2023
Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.
Sakthikumar S et al.
Veterinary and Comparative Oncology, 2023
New molecular targets in canine hemangiosarcoma-Comparative review and future of the precision medicine.
Kapturska KM et al.
Veterinary and Comparative Oncology, 2023
A frequent PLCγ1 mutation in adult T-cell leukemia/lymphoma determines functional properties of the malignant cells.
Prawiro C et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2023
Targeted panel sequencing in the routine diagnosis of mature T- and NK-cell lymphomas: report of 128 cases from two German reference centers.
Böck J et al.
Frontiers in Oncology, 2023
Mutations Affecting Genes in the Proximal T-Cell Receptor Signaling Pathway in Peripheral T-Cell Lymphoma.
Liu X et al.
Cancers, 2022
Advances in the understanding and treatment of Cutaneous T-cell Lymphoma.
Bakr FS et al.
Frontiers in Oncology, 2022
Targeted Deep Sequencing of Mycosis Fungoides Reveals Intracellular Signaling Pathways Associated with Aggressiveness and Large Cell Transformation.
Wobser M et al.
Cancers, 2021
Mutation analysis links angioimmunoblastic T-cell lymphoma to clonal hematopoiesis and smoking.
Cheng S et al.
Elife, 2021
Oncogenic Mutations and Gene Fusions in CD30-Positive Lymphoproliferations and Clonally Related Mycosis Fungoides Occurring in the Same Patients.
Wobser M et al.
Jid Innovations : Skin Science From Molecules to Population Health, 2021
Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma.
Yamagishi M et al.
Nature Communications, 2021
Mycosis Fungoides and Sézary Syndrome: An Integrative Review of the Pathophysiology, Molecular Drivers, and Targeted Therapy.
García-Díaz N et al.
Cancers, 2021
Targeted deep sequencing reveals clonal and subclonal mutational signatures in Adult T-cell leukemia/lymphoma and defines an unfavorable indolent subtype.
Marçais A et al.
Leukemia, 2021
Genetic profile of adult T-cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV-1 strains.
Sakihama S et al.
Cancer Science, 2021
A computational in silico approach to predict high-risk coding and non-coding SNPs of human PLCG1 gene.
Khan SM et al.
Plos One, 2021
Phospholipase C families: Common themes and versatility in physiology and pathology.
Katan M et al.
Progress in Lipid Research, 2020
Angioimmunoblastic T-cell lymphoma contains multiple clonal T-cell populations derived from a common TET2 mutant progenitor cell.
Yao WQ et al.
The Journal of Pathology, 2020
Frequent and Persistent PLCG1 Mutations in Sézary Cells Directly Enhance PLCγ1 Activity and Stimulate NFκB, AP-1, and NFAT Signaling.
Patel VM et al.
The Journal of Investigative Dermatology, 2020
Structural insights and activating mutations in diverse pathologies define mechanisms of deregulation for phospholipase C gamma enzymes.
Liu Y et al.
Ebiomedicine, 2020