Varaico: Literature-Extracted Genetic Variants

Gene:PLCZ1
Variant:p.S500L
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PLCZ1

NM_033123.4:p.S500L

Associated Papers

Novel PLCZ1 compound heterozygous mutations indicate gene dosage effect involved in total fertilisation failure after ICSI.

Li Q et al.

Reproduction (cambridge, England), 2024

High rate of detected variants in male PLCZ1 and ACTL7A genes causing failed fertilization after ICSI.

Cardona Barberán A et al.

Human Reproduction Open, 2024

Assisted oocyte activation does not overcome recurrent embryo developmental problems.

Cardona Barberán A et al.

Human Reproduction (oxford, England), 2023

SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1.

Thanassoulas A et al.

Reproduction (cambridge, England), 2022

Gene mutations associated with fertilization failure after in vitro fertilization/intracytoplasmic sperm injection.

Xue Y et al.

Frontiers in Endocrinology, 2022

Novel phospholipase C zeta 1 mutations associated with fertilization failures after ICSI.

Torra-Massana M et al.

Human Reproduction (oxford, England), 2019

PLCζ sequence, protein levels, and distribution in human sperm do not correlate with semen characteristics and fertilization rates after ICSI.

Ferrer-Vaquer A et al.

Journal of Assisted Reproduction and Genetics, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."