Varaico: Literature-Extracted Genetic Variants

Gene:PLCZ1
Variant:p.C196*
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PLCZ1

NM_033123.4:p.C196*

Associated Papers

PLCZ1 gene mutation leads to fertilization disorder: a case report.

Xiong Y et al.

Jbra Assisted Reproduction, 2025

Novel PLCZ1 compound heterozygous mutations indicate gene dosage effect involved in total fertilisation failure after ICSI.

Li Q et al.

Reproduction (cambridge, England), 2024

Defects in phospholipase C zeta cause polyspermy and low fertilization after conventional IVF: not just ICSI failure.

Che JF et al.

Asian Journal of Andrology, 2024

Exonic genetic variants associated with unexpected fertilization failure and zygotic arrest after ICSI: a systematic review.

Torra-Massana M et al.

Zygote (cambridge, England), 2023

Mutations in PLCZ1 induce male infertility associated with polyspermy and fertilization failure.

Peng Y et al.

Journal of Assisted Reproduction and Genetics, 2023

Novel mutations in PLCZ1 lead to early embryonic arrest as a male factor.

Lin Y et al.

Frontiers in Cell and Developmental Biology, 2023

SPERM FACTORS AND EGG ACTIVATION: Phospholipase C zeta (PLCZ1) and the clinical diagnosis of oocyte activation deficiency.

Jones C et al.

Reproduction (cambridge, England), 2022

SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1.

Thanassoulas A et al.

Reproduction (cambridge, England), 2022

Gene mutations associated with fertilization failure after in vitro fertilization/intracytoplasmic sperm injection.

Xue Y et al.

Frontiers in Endocrinology, 2022

Novel mutations in the PLCZ1 gene associated with human low or failed fertilization.

Yuan P et al.

Molecular Genetics & Genomic Medicine, 2020

A homozygous nonsense mutation of PLCZ1 cause male infertility with oocyte activation deficiency.

Wang F et al.

Journal of Assisted Reproduction and Genetics, 2020

The identification of novel mutations in PLCZ1 responsible for human fertilization failure and a therapeutic intervention by artificial oocyte activation.

Mu J et al.

Molecular Human Reproduction, 2020

Novel mutations in PLCZ1 cause male infertility due to fertilization failure or poor fertilization.

Yan Z et al.

Human Reproduction (oxford, England), 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."