Varaico: Literature-Extracted Genetic Variants

Gene:PLEKHA2
Variant:p.R218L
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PLEKHA2

NM_021623.2:p.R218L

Associated Papers

Identification of novel variants associated with osteoporosis, type 2 diabetes and potentially pleiotropic loci using pleiotropic cFDR method.

Hu Y et al.

Bone, 2018

Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.

Wullschleger S et al.

The Biochemical Journal, 2011

TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia.

Costantini JL et al.

Blood, 2009

TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor.

Marshall AJ et al.

Molecular and Cellular Biology, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."