Associated Papers
METTL16-mediated N6-methyladenosine modification of Soga1 enables proper chromosome segregation and chromosomal stability in colorectal cancer.
Li J et al.
Cell Proliferation, 2024
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation.
Sharma P et al.
Scientific Reports, 2019
PLK1 targets CtIP to promote microhomology-mediated end joining.
Wang H et al.
Nucleic Acids Research, 2018
Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity.
Kettenbach AN et al.
Science Signaling, 2018
MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1.
Zhao W et al.
The Journal of Cell Biology, 2016
The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores.
Lee HS et al.
Nature Communications, 2015
In-silico screening of cancer associated mutation on PLK1 protein and its structural consequences.
Kamaraj B et al.
Journal of Molecular Modeling, 2013
Plk1 regulates both ASAP localization and its role in spindle pole integrity.
Eot-Houllier G et al.
The Journal of Biological Chemistry, 2010
BubR1 localizes to centrosomes and suppresses centrosome amplification via regulating Plk1 activity in interphase cells.
Izumi H et al.
Oncogene, 2009
The regulatory beta-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis.
Yde CW et al.
Oncogene, 2008
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