Varaico: Literature-Extracted Genetic Variants

Gene:PLN
Variant:p.C41F
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PLN

NM_002667.5:p.C41F

Associated Papers

Pathological mutations in the phospholamban cytoplasmic region affect its topology and dynamics modulating the extent of SERCA inhibition.

Weber DK et al.

Biochimica Et Biophysica Acta. Biomembranes, 2024

Molecular noise filtering in the β-adrenergic signaling network by phospholamban pentamers.

Koch D et al.

Cell Reports, 2021

Atomistic Structure and Dynamics of the Ca2+-ATPase Bound to Phosphorylated Phospholamban.

Aguayo-Ortiz R et al.

International Journal of Molecular Sciences, 2020

Effects of the Arg9Cys and Arg25Cys mutations on phospholamban's conformational equilibrium in membrane bilayers.

Nelson SED et al.

Biochimica Et Biophysica Acta. Biomembranes, 2018

Effects of naturally occurring arginine 14 deletion on phospholamban conformational dynamics and membrane interactions.

Vostrikov VV et al.

Biochimica Et Biophysica Acta, 2015

Phosphorylation and mutation of phospholamban alter physical interactions with the sarcoplasmic reticulum calcium pump.

Glaves JP et al.

Journal of Molecular Biology, 2011

Comparing the structure and dynamics of phospholamban pentamer in its unphosphorylated and pseudo-phosphorylated states.

Oxenoid K et al.

Protein Science : a Publication of the Protein Society, 2007

Cross-linking of C-terminal residues of phospholamban to the Ca2+ pump of cardiac sarcoplasmic reticulum to probe spatial and functional interactions within the transmembrane domain.

Chen Z et al.

The Journal of Biological Chemistry, 2006

Pentameric assembly of phospholamban facilitates inhibition of cardiac function in vivo.

Chu G et al.

The Journal of Biological Chemistry, 1998

Cysteine reactivity and oligomeric structures of phospholamban and its mutants.

Karim CB et al.

Biochemistry, 1998

Structural organization of the pentameric transmembrane alpha-helices of phospholamban, a cardiac ion channel.

Arkin IT et al.

The Embo Journal, 1994

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."