Varaico: Literature-Extracted Genetic Variants

Gene:PML
Variant:p.S117A
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PML

NM_033238.3:p.S117A

Associated Papers

Phase separation is required for PML nuclear body biogenesis and function.

Wu W et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2023

An arginine-rich motif of ring finger protein 4 (RNF4) oversees the recruitment and degradation of the phosphorylated and SUMOylated Krüppel-associated box domain-associated protein 1 (KAP1)/TRIM28 protein during genotoxic stress.

Kuo CY et al.

The Journal of Biological Chemistry, 2014

Proteasome-dependent dispersal of PML nuclear bodies in response to alkylating DNA damage.

Conlan LA et al.

Oncogene, 2004

PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2.

Yang S et al.

Nature Cell Biology, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."