Varaico: Literature-Extracted Genetic Variants

Gene:PML
Variant:p.K160R
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PML

NM_033238.3:p.K160R

Associated Papers

TREX1 exonuclease in immunity and disease.

Shang Z et al.

International Immunology, 2025

Phase separation is required for PML nuclear body biogenesis and function.

Wu W et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2023

C-terminal motifs in promyelocytic leukemia protein isoforms critically regulate PML nuclear body formation.

Li C et al.

Journal of Cell Science, 2017

An arginine-rich motif of ring finger protein 4 (RNF4) oversees the recruitment and degradation of the phosphorylated and SUMOylated Krüppel-associated box domain-associated protein 1 (KAP1)/TRIM28 protein during genotoxic stress.

Kuo CY et al.

The Journal of Biological Chemistry, 2014

Dual roles for lysine 490 of promyelocytic leukemia protein in the transactivation of glucocorticoid receptor-interacting protein 1.

Liu ST et al.

Biochimica Et Biophysica Acta, 2013

Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1.

Bailey D et al.

The Journal of Biological Chemistry, 2004

Identification of three major sentrinization sites in PML.

Kamitani T et al.

The Journal of Biological Chemistry, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."