Varaico: Literature-Extracted Genetic Variants

Gene:PML
Variant:p.R175H
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PML

NM_033238.3:p.R175H

Associated Papers

Discovery of Drugs Targeting Mutant p53 and Progress in Nano-Enabled Therapeutic Strategy for p53-Mutated Cancers.

Zhang N et al.

Biomolecules, 2025

Targeting the p53 signaling pathway in cancers: Molecular mechanisms and clinical studies.

Shen J et al.

Medcomm, 2023

Regulation of p53 and Cancer Signaling by Heat Shock Protein 40/J-Domain Protein Family Members.

Kaida A et al.

International Journal of Molecular Sciences, 2021

Regulators of Oncogenic Mutant TP53 Gain of Function.

Yamamoto S et al.

Cancers, 2018

Mutant p53 partners in crime.

Kim MP et al.

Cell Death and Differentiation, 2018

Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.

De Smet F et al.

The Journal of Pathology, 2017

Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants.

Giorgi C et al.

Frontiers in Oncology, 2016

TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution.

Hou HA et al.

Blood Cancer Journal, 2015

TP53 mutants in the tower of babel of cancer progression.

Bisio A et al.

Human Mutation, 2014

Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53.

Martinez-Rivera M et al.

Biochemical Pharmacology, 2012

Tissue microarray cytometry reveals positive impact of homeodomain interacting protein kinase 2 in colon cancer survival irrespective of p53 function.

Soubeyran I et al.

The American Journal of Pathology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."