Associated Papers
Mutations at proximal cysteine residues in PML impair ATO binding by destabilizing the RBCC domain.
Dubey S et al.
The Febs Journal, 2024
Phase separation is required for PML nuclear body biogenesis and function.
Wu W et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2023
Identification of a point mutation PMLS214L-RARα that alters PML body organization, dynamics and SUMOylation.
Zhao S et al.
Biochemical and Biophysical Research Communications, 2019
Comprehensive mutational analysis of primary and relapse acute promyelocytic leukemia.
Madan V et al.
Leukemia, 2016
27063598 (PubMed )
Supplement: leu201669x7.xls › Sheet_1
Varying responses of PML-RARA with different genetic mutations to arsenic trioxide.
Liu J et al.
Blood, 2016
Evaluating frequency of PML-RARA mutations and conferring resistance to arsenic trioxide-based therapy in relapsed acute promyelocytic leukemia patients.
Lou Y et al.
Annals of Hematology, 2015
Secondary mutations as mediators of resistance to targeted therapy in leukemia.
Daver N et al.
Blood, 2015
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