Varaico: Literature-Extracted Genetic Variants

Gene:PML
Variant:p.A216T
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PML

NM_033238.3:p.A216T

Associated Papers

Mutations at proximal cysteine residues in PML impair ATO binding by destabilizing the RBCC domain.

Dubey S et al.

The Febs Journal, 2024

Mutational landscape of patients with acute promyelocytic leukemia at diagnosis and relapse.

Iaccarino L et al.

American Journal of Hematology, 2019

Mutations affecting both the rearranged and the unrearranged PML alleles in refractory acute promyelocytic leukaemia.

Iaccarino L et al.

British Journal of Haematology, 2016

Secondary mutations as mediators of resistance to targeted therapy in leukemia.

Daver N et al.

Blood, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."