Associated Papers
CDK-mediated phosphorylation of PNKP is required for end-processing of single-strand DNA gaps on Okazaki fragments and genome stability.
Tsukada K et al.
Elife, 2025
PNKP safeguards stalled replication forks from nuclease-dependent degradation during replication stress.
Mashayekhi F et al.
Cell Reports, 2024
CDK-dependent phosphorylation regulates PNKP function in DNA replication.
Mashayekhi F et al.
The Journal of Biological Chemistry, 2024
Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair.
Tahbaz N et al.
Nucleic Acids Research, 2012
The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase.
Garces F et al.
Molecular Cell, 2011
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