Associated Papers
Whole-Genome Sequencing Reveals a Novel GATA2 Mutation in Lower-Grade Glioma: Bioinformatics Analysis of Functional and Therapeutic Implications.
Handoko et al.
Cancers, 2025
Glucagon Receptor Deficiency Causes Early-Onset Hepatic Steatosis.
Cacciottolo TM et al.
Diabetes, 2025
Fifteen Years of PNPLA3: Transforming Hepatology Through Human Genetics.
Romeo S et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2025
Role of genetic variants and DNA methylation of lipid metabolism-related genes in metabolic dysfunction-associated steatotic liver disease.
Wang JJ et al.
Frontiers in Physiology, 2025
PNPLA3-Ile148Met and TM6SF2-Glu167Lys increase susceptibility to metabolic dysfunction-associated steatotic liver disease in children.
Yao H et al.
Frontiers in Endocrinology, 2025
Exome-wide association analysis of CT imaging-derived hepatic fat in a medical biobank.
Park J et al.
Cell Reports. Medicine, 2022
Molecular Screening via Sanger Sequencing of the Genetic Variants in Non-Alcoholic Fatty Liver Disease Subjects in the Saudi Population: A Hospital-Based Study.
Alsaif F et al.
Metabolites, 2022
A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction.
Nakajima R et al.
Endocrinology, Diabetes & Metabolism Case Reports, 2022
Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice.
Kabbani M et al.
Cell Reports, 2022
A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases.
Jian M et al.
Journal of Translational Medicine, 2020
Association between PNPLA3 gene polymorphisms and risk of hepatitis B virus-related hepatocellular carcinoma in Han population in China:a case-control study.
Gao X et al.
Scandinavian Journal of Gastroenterology, 2017
Screening for rare variants in the PNPLA3 gene in obese liver biopsy patients.
Zegers D et al.
Clinics and Research in Hepatology and Gastroenterology, 2016
Meta-analysis of the influence of TM6SF2 E167K variant on Plasma Concentration of Aminotransferases across different Populations and Diverse Liver Phenotypes.
Sookoian S et al.
Scientific Reports, 2016
Hepatic patatin-like phospholipase domain-containing protein 3 sequence, single nucleotide polymorphism presence, protein confirmation, and responsiveness to energy balance in dairy cows.
McCann CC et al.
Journal of Dairy Science, 2014
Next-generation sequence analysis of genes associated with obesity and nonalcoholic fatty liver disease-related cirrhosis in extreme obesity.
Gerhard GS et al.
Human Heredity, 2013
PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease.
Sookoian S et al.
World Journal of Gastroenterology, 2012
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Romeo S et al.
Nature Genetics, 2008
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.
Yuan X et al.
American Journal of Human Genetics, 2008