Associated Papers
Germline mutations and somatic mosaicism in steatotic liver diseases and related liver carcinogenesis.
Trépo E et al.
Nature Reviews. Gastroenterology & Hepatology, 2026
Fifteen Years of PNPLA3: Transforming Hepatology Through Human Genetics.
Romeo S et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2025
Molecular Characterization of Patatin-Like Phospholipase Domain-Containing 3 (PNPLA3) Gene in Alcoholic Liver Disease.
N S et al.
Cureus, 2025
Experimental Models to Investigate PNPLA3 in Liver Steatosis.
Ramandi A et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2025
Global Epidemiological Impact of PNPLA3 I148M on Liver Disease.
Kozlitina J et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2025
iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies.
Palasantzas VEJM et al.
Trends in Genetics : Tig, 2023
High-frequency variants in PKA signaling-related genes within a large pediatric cohort with obesity or metabolic abnormalities.
Bloyd M et al.
Frontiers in Endocrinology, 2023
Exome-wide association analysis of CT imaging-derived hepatic fat in a medical biobank.
Park J et al.
Cell Reports. Medicine, 2022
Contribution of a genetic risk score to ethnic differences in fatty liver disease.
Kubiliun MJ et al.
Liver International : Official Journal of the International Association for the Study of the Liver, 2022
PNPLA3 as a therapeutic target for fatty liver disease: the evidence to date.
Cherubini A et al.
Expert Opinion on Therapeutic Targets, 2021
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.
Palmer ND et al.
Human Molecular Genetics, 2021
Genetic and epigenetic disease modifiers: non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD).
Choudhary NS et al.
Translational Gastroenterology and Hepatology, 2021
Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug-Induced Liver Injury.
Bonkovsky HL et al.
Hepatology Communications, 2019
Obesity genetics and cardiometabolic health: Potential for risk prediction.
Sanghera DK et al.
Diabetes, Obesity & Metabolism, 2019
Genetic analysis of nonalcoholic fatty liver disease within a Caribbean-Hispanic population.
Edelman D et al.
Molecular Genetics & Genomic Medicine, 2015
PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease.
Shen J et al.
Journal of Gastroenterology and Hepatology, 2015
Host genetic variants in obesity-related nonalcoholic fatty liver disease.
Mehta R et al.
Clinics in Liver Disease, 2014
Hepatic patatin-like phospholipase domain-containing protein 3 sequence, single nucleotide polymorphism presence, protein confirmation, and responsiveness to energy balance in dairy cows.
McCann CC et al.
Journal of Dairy Science, 2014
PNPLA3-associated steatohepatitis: toward a gene-based classification of fatty liver disease.
Krawczyk M et al.
Seminars in Liver Disease, 2013
PNPLA3, the triacylglycerol synthesis/hydrolysis/storage dilemma, and nonalcoholic fatty liver disease.
Sookoian S et al.
World Journal of Gastroenterology, 2012
Genetic modifiers of non-alcoholic fatty liver disease progression.
Anstee QM et al.
Biochimica Et Biophysica Acta, 2011
Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease.
Huang Y et al.
The Journal of Biological Chemistry, 2011
Analysis of single nucleotide polymorphisms in case-control studies.
Li Y et al.
Methods in Molecular Biology (clifton, N.j.), 2011
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis.
He S et al.
The Journal of Biological Chemistry, 2010
Variant in PNPLA3 is associated with alcoholic liver disease.
Tian C et al.
Nature Genetics, 2010
[Polymorphisms in adiponutrin gene and association to hepatic steatosis].
Baulande S
Medecine Sciences : M/s, 2009
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Romeo S et al.
Nature Genetics, 2008