Associated Papers
Identifying Rare Germline Variants Associated with Metastatic Prostate Cancer Through an Extreme Phenotype Study.
Lin YY et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Study of sex-biased differences in genomic profiles in East Asian hepatocellular carcinoma.
Huang CY et al.
Discover Oncology, 2024
Mouse models to explore the biological and organismic role of DNA polymerase beta.
Sobol RW
Environmental and Molecular Mutagenesis, 2024
DNA polymerase beta connects tumorigenicity with the circadian clock in liver cancer through the epigenetic demethylation of Per1.
Chen S et al.
Cell Death & Disease, 2024
Mutation characteristics of cancer susceptibility genes in Chinese ovarian cancer patients.
Wang J et al.
Frontiers in Oncology, 2024
The Activity of Natural Polymorphic Variants of Human DNA Polymerase β Having an Amino Acid Substitution in the Transferase Domain.
Kladova OA et al.
Cells, 2023
The Role of Natural Polymorphic Variants of DNA Polymerase β in DNA Repair.
Kladova OA et al.
International Journal of Molecular Sciences, 2022
DNA Polymerase β in the Context of Cancer.
Sawyer DL et al.
Critical Reviews in Oncogenesis, 2022
R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities.
Laverde EE et al.
The Journal of Biological Chemistry, 2020
Trinucleotide repeat instability via DNA base excision repair.
Lai Y et al.
Dna Repair, 2020
Enhanced Activity of Variant DNA Polymerase β (D160G) Contributes to Cisplatin Therapy by Impeding the Efficiency of NER.
Wang M et al.
Molecular Cancer Research : Mcr, 2019
Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.
Fang Q et al.
Nucleic Acids Research, 2019
Whole-Exome Sequencing Characterized the Landscape of Somatic Mutations and Pathways in Colorectal Cancer Liver Metastasis.
Feng L et al.
Journal of Oncology, 2019
Loss of DNA polymerase β induces cellular senescence.
Ahmed AA et al.
Environmental and Molecular Mutagenesis, 2018
The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation.
Sun H et al.
Oncogene, 2017
Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q.
Ren Y et al.
Plos One, 2017
Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression.
He L et al.
Ebiomedicine, 2016
Association Study of a Proliferation-inducing Ligand, Spermatogenesis Associated 8, Platelet-derived Growth Factor Receptor-alpha, and POLB Polymorphisms with Systemic Lupus Erythematosus in Chinese Han Population.
Li P et al.
Chinese Medical Journal, 2016
Mutation of DNA Polymerase β R137Q Results in Retarded Embryo Development Due to Impaired DNA Base Excision Repair in Mice.
Pan F et al.
Scientific Reports, 2016
DNA polymerase β mutations and survival of patients with esophageal squamous cell carcinoma in Linzhou City, China.
Li M et al.
Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014
Cellular roles of DNA polymerase beta.
Ray S et al.
The Yale Journal of Biology and Medicine, 2013
The role of arginine methylation in the DNA damage response.
Auclair Y et al.
Dna Repair, 2013
Translesion DNA polymerases and cancer.
Makridakis NM et al.
Frontiers in Genetics, 2012
A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation.
Yamtich J et al.
Plos Genetics, 2012
Genome instability caused by a germline mutation in the human DNA repair gene POLB.
Sobol RW
Plos Genetics, 2012
Chemical-induced cancer incidence and underlying mechanisms in Fen1 mutant mice.
Xu H et al.
Oncogene, 2011
Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.
Guo Z et al.
Nucleic Acids Research, 2009
Population-specific variation in haplotype composition and heterozygosity at the POLB locus.
Yamtich J et al.
Dna Repair, 2009
[DNA polymerases beta and lambda, and their roles in the DNA replication and repair].
Belousova EA et al.
Molekuliarnaia Biologiia, 0