Associated Papers
DNA Polymerase β in the Context of Cancer.
Sawyer DL et al.
Critical Reviews in Oncogenesis, 2022
Revealing an Internal Stabilization Deficiency in the DNA Polymerase β K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.
Batra VK et al.
Biochemistry, 2020
Enhanced Activity of Variant DNA Polymerase β (D160G) Contributes to Cisplatin Therapy by Impeding the Efficiency of NER.
Wang M et al.
Molecular Cancer Research : Mcr, 2019
Approaches for Identifying Novel Targets in Precision Medicine: Lessons from DNA Repair.
Williams DT et al.
Advances in Experimental Medicine and Biology, 2017
A Point Mutation in DNA Polymerase β (POLB) Gene Is Associated with Increased Progesterone Receptor (PR) Expression and Intraperitoneal Metastasis in Gastric Cancer.
Tan X et al.
Journal of Cancer, 2016
The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency.
Nemec AA et al.
The Journal of Biological Chemistry, 2014
Cellular roles of DNA polymerase beta.
Ray S et al.
The Yale Journal of Biology and Medicine, 2013
DNA polymerase β promoter mutations and transcriptional activity in esophageal squamous cell carcinoma.
Li M et al.
Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013
Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation.
Nemec AA et al.
The Journal of Biological Chemistry, 2012
The E288K colon tumor variant of DNA polymerase β is a sequence specific mutator.
Murphy DL et al.
Biochemistry, 2012
The human gastric cancer-associated DNA polymerase β variant D160N is a mutator that induces cellular transformation.
Donigan KA et al.
Dna Repair, 2012
Genome instability caused by a germline mutation in the human DNA repair gene POLB.
Sobol RW
Plos Genetics, 2012
Is there a link between DNA polymerase beta and cancer?
Starcevic D et al.
Cell Cycle (georgetown, Tex.), 2004
Involvement of phylogenetically conserved acidic amino acid residues in catalysis by an oxidative DNA damage enzyme formamidopyrimidine glycosylase.
Lavrukhin OV et al.
Biochemistry, 2000
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