Varaico: Literature-Extracted Genetic Variants

Gene:POLB
Variant:p.K167I
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POLB

NM_002690.3:p.K167I

Associated Papers

The Link Between Human Alkyladenine DNA Glycosylase and Cancer Development.

Kladova OA et al.

International Journal of Molecular Sciences, 2025

Revealing an Internal Stabilization Deficiency in the DNA Polymerase β K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography.

Batra VK et al.

Biochemistry, 2020

Overexpression of A613T and G462T variants of DNA polymerase β weakens chemotherapy sensitivity in esophageal cancer cell lines.

Wang Y et al.

Cancer Cell International, 2016

The K167I variant of DNA polymerase β that is found in Esophageal Carcinoma patients impairs polymerase activity and BER.

Wang Y et al.

Scientific Reports, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."